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PEER-REVIEWED RESEARCH

Clinical Papers & Published Research

Validated by science. Trusted by physicians worldwide.

Backed by Rigorous Clinical Research

LIGHTMED laser technologies are supported by peer-reviewed publications across leading medical journals.

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Glaucoma

Selective laser trabeculoplasty and transscleral cyclophotocoagulation studies.

Selective Laser Trabeculoplasty Positively Impacts Long-Term Intraocular Pressure Fluctuation in Untreated Open-Angle Glaucoma Patients

SLT not only lowers mean IOP but also contributes to stabilizing IOP peak.

Frederico de Miranda Cordeiro, Maria Betânia Lemos, Ricardo Y. Abe, et al., Lasers in Medical Science, 2025

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Case Report: A Two-Step Approach in the Management of Angle-Closure Glaucoma Associated with Plateau Iris Configuration

Two-step approach using transscleral cyclophotocoagulation for angle-closure glaucoma management.

Tiago Santos Prata, Isabella Cristina Tristão Pinto Resende, et al., Arq Bras Oftalmol., 2025

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Selective Laser Trabeculoplasty as a Substitute for Medications in Patients with Mild-to-Moderate Glaucoma in the Brazilian Public Health System

68.19% of patients had a decrease in quantity of eye drops used after SLT treatment.

Leopoldo Ernesto Oiticica Barbosa, Wilma Lelis Barboza, et al., J Glaucoma, 2024

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Evaluation of Selective Laser Trabeculoplasty Effectiveness in Cases with Pseudoexfoliation Glaucoma and Ocular Hypertension

Single session of 180° SLT as primary treatment in newly diagnosed pseudoexfoliation glaucoma (36 cases) and ocular hypertension (32 cases).

Hakan Ozturk, Bediz Ozen, European Eye Research, 2024

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Comparison of the Short-Term Results of Nasal and Temporal 180° Selective Laser Trabeculoplasties for Open-Angle Glaucoma

Prospective comparison of nasal versus temporal 180° SLT application and IOP reduction outcomes.

Jayter Silva Paula, Cassia Senger, Carlos Gustavo de Moraes, Arq Bras Oftalmol., 2023

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The Effectiveness of Laser Peripheral Iridotomy in Adolescent Eyes with Ocular Hypertension and Concave Configuration of the Peripheral Iris

Effectiveness of Nd:YAG laser peripheral iridotomy in adolescent eyes with ocular hypertension and concave peripheral iris configuration.

Alina Bakunowicz-Lazarczyk, Beata Urban, Malgorzata Kretowska, Journal of Ophthalmology, 2022

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Comparison of the Effects of 180° and 360° Applications of Selective Laser Trabeculoplasty on Intraocular Pressure and Cornea

180° and 360° SLT are similarly effective in reducing IOP.

Bediz Ozen, Hakan Ozturk, Berna Yuce, Int Ophthalmol., 2020

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Selective Laser Trabeculoplasty vs Micropulse Laser Trabeculoplasty for the Treatment of Open Angle Glaucoma and Ocular Hypertension

Comparative study evaluating SLT versus micropulse laser trabeculoplasty for open-angle glaucoma and ocular hypertension.

Marcela Irene De Leon De Leon, Jose Francisco Ortega Santana, Alfonso Garcia Lopez, Int J Research in Medical and Health Sciences, 2017

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Retina

SP-Mode® sub-threshold laser and multi-wavelength photocoagulation studies.

Subthreshold Laser Therapy for CSCR

577 nm subthreshold laser therapy is a viable option for treating CSCR.

Rami Madani, Adam Ayoub, Tarek Alasil, Retina Today, 2024

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Comparison of One-Year Real-World Outcomes Between Red (670 nm) Subthreshold Micropulse Laser Treatment and Intravitreal Aflibercept Injection for Treatment-Naïve Diabetic Macular Edema

Red SMPL treatment outcomes were equivalent to IVA in real-world settings.

Wataru Kikushima, Yukiko Furuhata, Taiyo Shijo, et al., Photodiagnosis and Photodynamic Therapy, 2025

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Hybrid Threshold Laser to Treat Diabetic Macular Edema: A Retrospective Analysis Single Center Cohort Study

Reduction of retinal thickness without significant changes of visual acuity.

Ameen Marashi, Aya Zazo, Annals of Medicine and Surgery, 2022

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Choosing the Right Wavelength: Effectiveness of Yellow

SP-Mode® has a better safety profile when treating the central macula.

Dr. Tarek Alasil, Retina Today, 2020

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Going Green – Treatment Outcome and Safety Profile of Chronic Central Serous Chorioretinopathy Treated with Subthreshold Green Laser

Green laser is a safe and effective modality with very good and stable outcomes.

Anadi Khatri, Eli Pradhan, Sweta Singh, et al., Clinical Ophthalmology, 2018

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Comparison of the 1-Year Visual and Anatomical Outcomes Between Subthreshold Red (670 nm) and Yellow (577 nm) Micro-Pulse Laser Treatment for Diabetic Macular Edema

Comparison of 1-year visual and anatomical outcomes between subthreshold red (670 nm) and yellow (577 nm) micropulse laser treatment for DME.

Wataru Kikushima, Taiyo Shijo, Yukiko Furuhata, Yoichi Sakurada, Kenji Kashiwagi, Pharmaceuticals, 2021

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Short-Term Outcome (1 Year) of Yellow Subthreshold Pulsed Laser Treatment on Diabetic Macular Edema

Short-term outcome (1 year) of yellow subthreshold pulsed laser treatment on diabetic macular edema.

Wataru Kikushima, Yasushi Tateno, Yukiko Furuhata, Taiyo Shijo, 36th Annual Meeting, Japanese Society for Ocular Circulation, 2019

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Comparison of Intravitreal Bevacizumab Alone Versus Combined Bevacizumab and Macular Photocoagulation in Diabetic Macular Edema

Comparison of intravitreal bevacizumab alone versus combined bevacizumab and macular photocoagulation in diabetic macular edema.

Çetin Akpolat, Ferhat Evliyaoğlu, Muhammed Mustafa Kurt, Burak Erden, Mustafa Nuri Elçioğlu, Turkey Clinical J Ophthalmol, 2018

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Sub-Threshold Micropulse Yellow 577 Laser Treatment of Retinal Diseases

Clinical applications of sub-threshold micropulse yellow 577 nm laser treatment across retinal diseases.

Dr. Igor Remesnikov, Astana Vision, Kazakhstan, 2017

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YAG Photodisruption

Nd:YAG laser applications in capsulotomy, iridotomy, and hyaloidotomy.

The Benefits of Nd:YAG Hyaloidotomy in the Management of Subhyaloid Retinal Hemorrhage

Nd:YAG laser hyaloidotomy is a relatively safe, office-based procedure.

Gafar Folohunso Yusuf, Gbemisola Racheal Borisade, Ojoma Sopuruchi Onyeka, Niger J Ophthalmol, 2024

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Quality of Life Results After Vitreolysis in Patients with Symptomatic Vitreous Floaters

Quality of life results after vitreolysis in patients with symptomatic vitreous floaters.

Renzo Cañote, Daniela Rodríguez, Luis Izquierdo Jr, Roger Moncada, Carmen Maldonado, Maria Alejandra Henriquez, The Pan-American Journal of Ophthalmology, 2020

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Objective Assessment of YAG Laser Vitreolysis in Patients with Symptomatic Vitreous Floaters

Objective assessment of YAG laser vitreolysis in patients with symptomatic vitreous floaters.

Carlos E. Souza, Luiz H. Lima, Heloísa Nascimento, Claudio Zett, Rubens Belfort Jr, International Journal of Retina and Vitreous, 2020

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The Results of the Treatment of Floating Opacities of the Vitreous Body Using a YAG Laser System with a Coaxial Light Divider

Results of treating floating opacities of the vitreous body using a YAG laser system with a coaxial light divider.

B.M. Aznabaev, T.R. Mukhamadeev, A.A. Alexandrov, T.I. Dibaev, A.S. Vafiev, I.Kh. Shavaliev, Ophthalmology, 2018

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Nd:YAG Laser Subretinal Membranotomy in Young Patients with Long-Term Retinal Detachment

YAG laser subretinal membranotomy in young patients with long-term retinal detachment.

C-H Peng, S-J Chen, C-C Tsai, F-L Lee, S-H Chiou, W-M Hsu, Eye, 2007

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Er:YAG Dental Laser Applications

SAPPHIRE Er:YAG laser studies in peri-implantitis, crown lengthening, and hard tissue ablation.

The “Er:YAG Laser-Assisted Periimplantitis Total Therapy (Er:LPTT)” – A Novel Procedure to Perform Periimplantitis Treatment with Bone Regeneration Therapy

Novel procedure combining implant surface debridement and granulation tissue removal.

Teichen Lin, Yoichi Taniguchi, Akira Aoki, Chun-Cheng Chen, Journal of Dental Sciences, 2021

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Er:YAG Laser-Assisted Flapless Esthetic Crown Lengthening Procedure: A Case Report

Minimally invasive, flapless esthetic crown lengthening approach.

Min Yes Ng, Taichen Lin, Cheng-Chia Yu, Chun-Cheng Chen, Journal of Dental Sciences, 2021

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In Vitro Laser Treatment Platform Construction with Dental Implant Thread Surface on Bacterial Adhesion for Peri-Implantitis

Sterilization rate can reach 99.3%.

Hsien-Nan Kuo, Hsiang-I Mei, Tung-Kuan Liu, et al., Hindawi BioMed Research International, 2017

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Application of Er:YAG Laser in the Treatment of Dentine Hypersensitivity

Application of Er:YAG laser in the treatment of dentine hypersensitivity.

Jung-Chang Kung, Chern-Hsiung Lai, Kun-Tsung Lee, Po-Sung Fu, Jeng-Hao Chen, I-Jui Chen, Dah-You Yan, Cheng-Chu Wang, You-Syun Jheng, Yi-Min Wu, Kaohsiung Medical University Hospital

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Application of Er:YAG Laser in the Treatment of Dental Caries

Application of Er:YAG laser in the treatment of dental caries.

Kun-Tsung Denzel Lee, Jung-Chang Kung, Chern-Hsiung Lai, Po-Sung Fu, I-Jui Chen, Dah-You Yan, Cheng-Chu Wang, You-Syun Jheng, Yi-Min Wu, International Congress on Adhesive Dentistry, Kaohsiung Medical University, 2019

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KTP Dermatology Laser Applications

DermaLight laser for vascular and pigmented lesion treatment.

Affordable DermaLight KTP Laser Delivers High Efficacy and Ease of Use

Clinical assessment of 532nm wavelength for telangiectasia, rosacea, and pigmented lesion treatment.

Jeffrey Frentzen, The Aesthetic Guide, 2017

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DermaLight Diode Laser Provides Solutions for Pigmented and Vascular Lesions

Clinical applications of DermaLight in facial cosmetic procedures and vascular treatments.

Kevin A. Wilson, The Aesthetic Guide, 2015

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