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PEER-REVIEWED RESEARCH

Clinical Papers & Published Research

Validated by science. Trusted by physicians worldwide.

Backed by Rigorous Clinical Research

LIGHTMED laser technologies are supported by peer-reviewed publications across leading medical journals.

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Glaucoma

Selective laser trabeculoplasty and transscleral cyclophotocoagulation studies.

Selective Laser Trabeculoplasty and IOP Fluctuation

SLT not only lowers mean IOP but also contributes to stabilizing IOP peak.

Frederico de Miranda Cordeiro, Maria Betânia Lemos, Ricardo Y. Abe, et al., Lasers in Medical Science, 2025

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Angle-Closure Glaucoma Management

Two-step approach using transscleral cyclophotocoagulation for angle-closure glaucoma management.

Tiago Santos Prata, Isabella Cristina Tristão Pinto Resende, et al., Arq Bras Oftalmol., 2025

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SLT as Medication Substitute

68.19% of patients had a decrease in quantity of eye drops used after SLT treatment.

Leopoldo Ernesto Oiticica Barbosa, Wilma Lelis Barboza, et al., J Glaucoma, 2024

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SLT Effectiveness in Pseudoexfoliation Glaucoma and Ocular Hypertension

Single session of 180° SLT as primary treatment in newly diagnosed pseudoexfoliation glaucoma (36 eyes) and ocular hypertension (32 eyes).

Hakan Ozturk, Bediz Ozen, European Eye Research, 2024

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Nasal vs. Temporal 180° SLT for Open-Angle Glaucoma

Prospective comparison of nasal versus temporal 180° SLT application and IOP reduction outcomes.

Jayter Silva Paula, Cassia Senger, Carlos Gustavo de Moraes, Arq Bras Oftalmol., 2023

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Laser Peripheral Iridotomy in Adolescent Ocular Hypertension

Effectiveness of Nd:YAG laser peripheral iridotomy in adolescent eyes with ocular hypertension and concave peripheral iris configuration.

Alina Bakunowicz-Lazarczyk, Beata Urban, Malgorzata Kretowska, Journal of Ophthalmology, 2022

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180° vs. 360° SLT Applications

180° and 360° SLT are similarly effective in reducing IOP.

Bediz Ozen, Hakan Ozturk, Berna Yuce, Int Ophthalmol., 2020

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SLT vs. Micropulse Laser Trabeculoplasty

Comparative study evaluating SLT versus micropulse laser trabeculoplasty for open-angle glaucoma and ocular hypertension.

Marcela Irene De Leon De Leon, Jose Francisco Ortega Santana, Alfonso Garcia Lopez, Int J Research in Medical and Health Sciences, 2017

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Retina

SP-Mode® sub-threshold laser and multi-wavelength photocoagulation studies.

Subthreshold Laser for Central Serous Chorioretinopathy

577 nm subthreshold laser therapy is a viable option for treating CSCR.

Rami Madani, Adam Ayoub, Tarek Alasil, Retina Today, 2024

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Red Micropulse Laser vs. Aflibercept for DME

Red SMPL treatment outcomes were equivalent to IVA in real-world settings.

Wataru Kikushima, Yukiko Furuhata, Taiyo Shijo, et al., Photodiagnosis and Photodynamic Therapy, 2025

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Hybrid Threshold Laser for Diabetic Macular Edema

Reduction of retinal thickness without significant changes of visual acuity.

Ameen Marashi, Aya Zazo, Annals of Medicine and Surgery, 2022

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Yellow Wavelength Effectiveness

SP-Mode® has a better safety profile when treating the central macula.

Dr. Tarek Alasil, Retina Today, 2020

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Green Subthreshold Laser for CSCR

Green laser is a safe and effective modality with very good and stable outcomes.

Anadi Khatri, Eli Pradhan, Sweta Singh, et al., Clinical Ophthalmology, 2018

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Red vs. Yellow Micropulse Laser for Diabetic Macular Edema

Comparison of 1-year visual and anatomical outcomes between subthreshold red (670 nm) and yellow (577 nm) micropulse laser treatment for DME.

Wataru Kikushima, Taiyo Shijo, Yukiko Furuhata, Yuki Sakurada, Kengo Kashiwagi, Pharmaceuticals, 2021

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Yellow Subthreshold Pulsed Laser for Diabetic Macular Edema

Short-term outcome (1 year) of yellow subthreshold pulsed laser treatment on diabetic macular edema.

Wataru Kikushima, Akira Tateno, Yukiko Furuhata, Taiyo Shijo, 36th Annual Meeting, Japanese Society for Ocular Circulation, 2019

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Bevacizumab Alone vs. Combined Bevacizumab and Macular Photocoagulation for DME

Comparison of intravitreal bevacizumab alone versus combined bevacizumab and macular photocoagulation in diabetic macular edema.

Cem Akpolat, Nihal Evliyaoğlu, Ebru Kurt, Burak Erden, Mustafa Nuri Elcioğlu, Turkey Clinical J Ophthalmol, 2018

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Sub-Threshold Micropulse Yellow 577 Laser for Retinal Diseases

Clinical applications of sub-threshold micropulse yellow 577 nm laser treatment across retinal diseases.

Remesnikov, Astana Vision, Kazakhstan, 2017

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YAG Photodisruption

Nd:YAG laser applications in capsulotomy, iridotomy, and hyaloidotomy.

Nd:YAG Hyaloidotomy for Subhyaloid Hemorrhage

Nd:YAG laser hyaloidotomy is a relatively safe, office-based procedure.

Gafar Folohunso Yusuf, Gbemisola Racheal Borisade, Ojoma Sopuruchi Onyeka, Niger J Ophthalmol, 2024

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Quality of Life after YAG Laser Vitreolysis

Quality of life results after vitreolysis in patients with symptomatic vitreous floaters.

Eduardo Cañote, Julio Rodríguez, Jorge Izquierdo Jr, Diana Moncada, Rafael Maldonado, Marcela Henriquez, The Pan-American Journal of Ophthalmology, 2020

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Objective Assessment of YAG Laser Vitreolysis

Objective assessment of YAG laser vitreolysis in patients with symptomatic vitreous floaters.

Caroline E. Souza, Leandro C. Lima, Marcos A. Nascimento, Cristiano Zett, Rubens Belfort Jr, International Journal of Retina and Vitreous, 2020

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Treatment of Floating Opacities Using YAG Laser with Coaxial Light Divider

Results of treating floating opacities of the vitreous body using a YAG laser system with a coaxial light divider.

Aznabaev, Mukhamadeev, Alexandrov, Dibaev, Vafiev, Shavaliev, Ophthalmology, 2018

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YAG Laser Subretinal Membranotomy

YAG laser subretinal membranotomy in young patients with long-term retinal detachment.

Keng-Hung Peng, Chun-Ju Chen, Chi-Chun Tsai, Shih-Ming Lee, Shiu-Hua Chiou, Ming-Hui Hsu, Eye, 2007

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Er:YAG Dental Laser Applications

SAPPHIRE Er:YAG laser studies in peri-implantitis, crown lengthening, and hard tissue ablation.

Er:YAG Laser-Assisted Periimplantitis Total Therapy

Novel procedure combining implant surface debridement and granulation tissue removal.

Teichen Lin, Yoichi Taniguchi, Akira Aoki, Chun-Cheng Chen, Journal of Dental Sciences, 2021

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Er:YAG Flapless Esthetic Crown Lengthening

Minimally invasive, flapless esthetic crown lengthening approach.

Min Yes Ng, Taichen Lin, Cheng-Chia Yu, Chun-Cheng Chen, Journal of Dental Sciences, 2021

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In Vitro Laser Treatment for Peri-Implantitis

Sterilization rate can reach 99.3%.

Hsien-Nan Kuo, Hsiang-I Mei, Tung-Kuan Liu, et al., Hindawi BioMed Research International, 2017

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Er:YAG Laser for Dentine Hypersensitivity

Application of Er:YAG laser in the treatment of dentine hypersensitivity.

Yung-Chun Kung, Yu-Lin Lai, Yen-Li Lee, Erh Fu, Chun-Cheng Chen, Yi-Wen Chen, Fu-Hsiung Yan, Chia-Tze Kao Wang, Yi-Jyun Jheng, Yueh-Chiao Wu, Kaohsiung Medical University Hospital

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Er:YAG Laser for Dental Caries

Application of Er:YAG laser in the treatment of dental caries.

Yen-Li Lee, Yung-Chun Kung, Yu-Lin Lai, Erh Fu, Chun-Cheng Chen, Fu-Hsiung Yan, Chia-Tze Kao Wang, Yi-Jyun Jheng, Yueh-Chiao Wu, International Congress on Adhesive Dentistry, Kaohsiung Medical University, 2019

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KTP Dermatology Laser Applications

DermaLight laser for vascular and pigmented lesion treatment.

DermaLight KTP Laser Efficacy

Clinical assessment of 532nm wavelength for telangiectasia, rosacea, and pigmented lesion treatment.

Jeffrey Frentzen, The Aesthetic Guide, 2017

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DermaLight Diode Laser Applications

Clinical applications of DermaLight in facial cosmetic procedures and vascular treatments.

Kevin A. Wilson, The Aesthetic Guide, 2015

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